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How to inject your GLP-1 pen the right way

How to inject your GLP-1 pen the right way

Your GLP-1 weight-loss pen goes under the skin, not into a muscle. Learn the three safe spots, the simple pen steps, and why your doctor should show you first.

13 Jul 2026 · Burnie Academy
glp-1 injection self-care weight-loss-medicines

You just got your GLP-1 pen. Now you wonder, how do I inject this? Do not worry. The pen is made for people to use at home. It goes just under your skin. This guide walks you through the safe way. Always keep your own pen's leaflet nearby. Your doctor or pharmacist should show you the first time.

Where the pen goes (and where it does not)

These pens go under your skin. This is called a subcutaneous injection. The medicine slowly reaches your body from there. Never push the medicine into a muscle or a vein. That is not how these pens work. Each pen's label lists three safe spots. They are your stomach (abdomen), the front of your thigh, or your upper arm. The upper arm spot usually needs a helper. Someone else injects there for you. Rotate your spots each time. Do not use the same place twice in a row.

Three pens, three simple plans

Wegovy (semaglutide)
Once a week, any time of day, with or without food. Comes as a single-dose pen or a multi-dose FlexTouch pen.
Saxenda (liraglutide)
Once a day, any time of day, with or without food. Comes as a multi-dose pen that gives many daily doses.
Mounjaro (tirzepatide)
Once a week, any time of day, with or without food. Comes as a single-dose pen, a vial, or a multi-dose KwikPen.

Injecting into a muscle makes the medicine work faster.

mostly false

Mostly false. These pens are made to go under the skin only. The Wegovy, Saxenda, and Mounjaro labels all warn not to inject into a muscle or a vein. Under the skin is the safe and correct way. Talk to your doctor if you feel the pen is not working for you.

The bottom line

Your pen goes under the skin on your stomach, thigh, or upper arm. Never inject into a muscle or a vein. Rotate spots each time, use a new needle, and count slowly to 6. Read your own pen's leaflet, and let your doctor or pharmacist show you the first time. When in doubt, ask them.

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